Peripherally inserted central catheters (PICCs) have a wide range of applications and are commonly used for delivering chemotherapy, antibiotics and for drawing blood. PICCs are introduced through the basilic, cephalic or median cubital veins in the arm and the tip of the catheter is then directed to the superior vena cava (SVC). Generally, the devices are used for one week to three months but can range in use from a few days to over a year. This flexibility sets PICCs apart from other vascular access catheters and contributes to the increased use of PICCs in general.